Malaria Immunology

The Immunology of Malaria

The main impetus for trying to understand immunity to malaria is the need to develop effective malaria vaccines. Despite years of knowing that humans can be immune to malaria the mechanisms underlying this immunity are yet to be properly understood. This is, in part, attributable to the complexity of the malaria parasite and its life cycle resulting in a complex parasite-host relation. The outc...

Immunology

Immunology.

The pathological changes involved in the immunological lung diseases of the bronchiolar region are reviewed. Next, the possibility that BOOP and DPB, two diseases whose causes are presently unknown, are caused by immune responses, is discussed.

Immunology

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

Background: The timing of infection is closely determined in controlled human malaria infection (CHMI) studies, and as such they provide a unique opportunity to dissect changes in immunological responses before and after a single infection. The first Kenyan Challenge Study (KCS) (Pan African Clinical Trial Registry: PACTR20121100033272) was performed in 2013 with the aim of establishing the CHM...